Biological Aspects of Suicidal Behavior
Editor(s): Kaschka W.P. (Ulm/Ravensburg)
Rujescu D. (Halle)
Publication year: 2016
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Advances in Biological Psychiatry , Vol. 30
Editor(s): Kaschka W.P. (Ravensburg)
Gattaz W.F. (São Paulo)
X + 170 p., 4 fig., 4 in color, 6 tab., hard cover, 2016
In recent years, the tools of modern neurosciences have increasingly been utilized to characterize the pathophysiology of complex human behaviors such as suicide. To improve suicide risk assessment and suicide prevention, a better understanding of its pathophysiology is crucial. This includes research from a variety of disciplines such as neuropsychological, psychosocial and cultural studies but also findings from biochemistry, neuropathology, electrophysiology, immunology, neuroimaging, genetics, and epigenetics. Important results have, for example, been obtained in the field of gene-environment interaction and suicidal behavior. We have just begun to understand how early-life adversity may increase suicide risk by epigenetic mechanisms. Based on such insights, novel therapeutic interventions and preventive measures can be developed. Furthermore, a better understanding of the pathophysiological mechanisms involved in suicidal behavior could reveal the mechanism of compounds like lithium salts. In this book, suicidal behavior and its prevention is discussed by international experts in the light of the most recent results from a broad spectrum of neurosciences.